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2-methyl-2-butanol inhibits binding to a proconvulsant site on the gaba receptor which causes negatively charged chloride ions to enter neurons and increase the amount of excitation necessary to cause the neurons to fire. as it is a tertiary alcohol, it cannot be metabolized by alcohol dehydrogenase into aldehydes (which cause the hangover associated with consuming large amounts of ethanol). this makes 2m2b significantly safer than primary alcohols. however, a consequence of this is that 2-methyl-2-butanol has an extended duration of action with effects which last up to 12 hours after its consumption.

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