2-fluoromethamphetamine (2-fma) is a novel stimulant substance of the amphetamine class. 2-fma is a member of a group known as substituted amphetamines, which include compounds like 2-fa, 3-fa, and 4-fma. 2-fma produces its stimulant effects through action at dopamine and norepinephrine receptors in the brain.
2-fma is commonly taken either orally or via insufflation and is reported to be highly unpleasant to vaporize. it is commonly compared to lisdexamfetamine (vyvanse) in its duration, potency and efficacy as a study or productivity aid. despite its popularity as a research chemical study aid, little is known about the effects that may accompany its long-term use as a substitute for prescription stimulants.
typical effects include those of a classical stimulant such as stimulation, enhanced focus and euphoria. a substantial increase in adverse effects like high blood pressure and increased heart rate are often reported for dosages above the heavy dosage range.
2-fluoromethamphetamine (2-fma) is a synthetic molecule of the substituted amphetamine class. molecules of the amphetamine class contain a phenethylamine core featuring a phenyl ring bound to an amino (nh2) group through an ethyl chain with an additional methyl substitution at rα (i.e., amphetamines are alpha-methylated phenethylamines). 2-fma contains a methyl group bound to the terminal amine rn of the amphetamine core, a substitution it shares with methamphetamine.
although 2-fma has not been formally studied on the same level as traditional amphetamines, it is thought that it acts as both a dopamine and norepinephrine releasing agent. this means it effectively increases the levels of the norepinephrine and dopamine in the brain by binding to and partially blocking the transporter proteins that normally remove them from the synaptic cleft. this allows dopamine and norepinephrine to accumulate within the brain, resulting in stimulating and euphoric effects.